| 20:45 | Clermont  Lens |  |
| 21:00 | Arsenal  West Bromwich Albion |  |
| 20:45 | Borussia Dortmund  Real Madrid |  |
| 20:45 | Monaco  FC Porto |  |
| 18:00 | Qarabağ  AS Roma |  |
| 20:45 | Atlético Madrid  Chelsea | |
| 20:45 | Sporting CP  FC Barcelone | |
| 20:45 | PSG  Bayern Munich |  |
| 19:00 | Nice  Vitesse | |
| 19:00 | Salzbourg  Olympique de Marseille | |
| 21:05 | Milan AC  Rijeka | |
| 21:05 | Olympique Lyonnais  Atalanta |  |
| 20:00 | Niort  Quevilly |  |
| 20:00 | Orléans  Valenciennes |  |
| 20:00 | Nancy  Châteauroux |  |
| 20:00 | Paris FC  Nîmes |  |
| 20:00 | Lens Gazélec Ajaccio |  |
| 20:00 | AJ Auxerre  Sochaux |  |
| 20:00 | AC Ajaccio  Bourg-Péronnas |  |
| 20:30 | Schalke 04  Bayer Leverkusen | |
| 20:45 | Monaco Montpellier | |
| 13:30 | Huddersfield Town  Tottenham Hotspur | |
| 15:00 | Reims Clermont | |
| 16:00 | Manchester United  Crystal Palace | |
| 17:00 | PSG Bordeaux | |
| 18:30 | Chelsea Manchester City | |
| 18:30 | Hambourg SV  Werder Brême | |
| 18:30 | Galatasaray  Karabükspor | |
| 20:00 | Stade Rennais  Caen | |
| 20:00 | Nantes  Metz | |
| 20:00 | Amiens SC  Lille | |
| 20:00 | Dijon  Strasbourg | |
| 20:00 | Guingamp  Toulouse | |
| 20:45 | Leganes Atlético Madrid | |
| 22:00 | Orlando City  Dallas |  |
| 12:30 | Naples  Cagliari | |
| 13:00 | Arsenal Brighton & Hove Albion | |
| 13:15 | Sheffield Wednesday  Leeds United | |
| 13:30 | Fribourg  Hoffenheim | |
| 15:00 | Chievo  Fiorentina | |
| 15:00 | Bénévent  Internazionale | |
| 15:00 | Lazio  Sassuolo | |
| 15:00 | Troyes  Saint-Étienne | |
| 15:15 | Everton  Burnley | |
| 15:30 | Hertha BSC Bayern Munich | |
| 16:15 | FC Barcelone Las Palmas | |
| 17:00 | Angers Olympique Lyonnais | |
| 17:30 | Newcastle United  Liverpool | |
| 18:00 | Cologne  RB Leipzig | |
| 18:00 | Milan ACAS Roma | |
| 18:30 | Valence  Athletic Bilbao | |
| 18:30 | Besiktas  Trabzonspor | |
| 19:00 | Philadelphie Union  Seattle Sounders |  |
| 20:15 | Sporting CPFC Porto |  |
| 20:45 | Atalanta Juventus | |
| 20:45 | Real Madrid Espanyol | |
| 21:00 | NiceOlympique de Marseille | |
| 22:30 | Maritimo  Benfica | |
