| 20:30 | AS Roma  Bologne |  |
| 20:30 | Nuremberg  Borussia Dortmund |  |
| 20:30 | Chelsea  Manchester United |  |
| 20:45 | Metz  Béziers |  |
| 21:00 | Huesca  Athletic Bilbao |  |
| 21:15 | Desportivo Aves  Benfica |  |
| 21:00 | Liverpool  Bayern Munich |  |
| 21:00 | Olympique Lyonnais  FC Barcelone |  |
| 18:00 | FC Séville  Lazio | |
| 19:00 | Bordeaux  Guingamp | |
| 21:00 | Atlético Madrid  Juventus | |
| 21:00 | Schalke 04  Manchester City |  |
| 21:00 | PSG  Montpellier |  |
| 01:00 | Boca Juniors  Atlético Tucumán | |
| 18:55 | Salzbourg  Club Bruges |  |
| 18:55 | Dinamo Zagreb  Viktoria Plzeň |  |
| 18:55 | Eintracht Francfort  FC Shakhtar Donetsk |  |
| 18:55 | Zenit  Fenerbahçe |  |
| 18:55 | Naples  FC Zürich |  |
| 18:55 | Villarreal  Sporting CP |  |
| 18:55 | Valence  Celtic Glasgow FC | |
| 18:55 | Arsenal  BATE | |
| 20:30 | Boulogne  Chambly |  |
| 21:00 | FC Dynamo Kiev  Olympiakos Pirée | |
| 21:00 | Inter Milan  Rapid Vienne | |
| 21:00 | Bayer Leverkusen  Krasnodar | |
| 21:00 | Genk  Slavia Prague | |
| 21:00 | Bétis Séville  Stade Rennais | |
| 21:00 | Chelsea Malmö FF | |
| 21:00 | Benfica Galatasaray | |
| 19:00 | Dijon  Saint-Étienne | |
| 20:00 | Red Star  Valenciennes |  |
| 20:00 | Orléans  Sochaux | |
| 20:00 | Troyes  Le Havre | |
| 20:00 | Béziers Châteauroux | |
| 20:00 | AC Ajaccio  AJ Auxerre | |
| 20:00 | Metz Paris FC | |
| 20:00 | Nancy  Gazélec Ajaccio |  |
| 20:00 | Brest  Grenoble Foot 38 | |
| 20:00 | Clermont  Lorient |  |
| 20:30 | La Gantoise  Standard de Liège |  |
| 20:30 | Milan AC  Empoli |  |
| 20:30 | Werder Brême  Stuttgart |  |
| 20:45 | West Ham United  Fulham | |
| 20:45 | Strasbourg  Lille | |
| 22:15 | Tondela  FC Porto | |
| 13:00 | Getafe  Rayo Vallecano | |
| 13:30 | Burnley  Tottenham Hotspur | |
| 15:00 | Torino  Atalanta | |
| 15:30 | Borussia M'gladbach  Wolfsbourg | |
| 15:30 | Mainz 05 Schalke 04 | |
| 15:30 | Bayern Munich Hertha BSC | |
| 16:00 | Leeds United  Bolton Wanderers | |
| 16:15 | FC SévilleFC Barcelone | |
| 17:00 | PSG Nîmes | |
| 18:30 | Leicester City  Crystal Palace | |
| 20:00 | Guingamp Angers | |
| 20:00 | Amiens SC  Nice | |
| 20:30 | Frosinone AS Roma | |
| 20:45 | Athletic Bilbao Eibar | |
| 01:30 | Independiente  Racing Club | |
| 12:00 | Leganes Valence | |
| 12:15 | ADO Den Haag  Ajax | |
| 12:30 | Sampdoria  Cagliari | |
| 14:30 | Anderlecht Club Bruges | |
| 15:00 | BologneJuventus | |
| 15:00 | Sassuolo  SPAL | |
| 15:00 | Montpellier Reims | |
| 15:00 | Toulouse  Caen | |
| 15:00 | Nantes Bordeaux | |
| 15:05 | Manchester UnitedLiverpool | |
| 15:30 | Hanovre 96 Eintracht Francfort | |
| 16:15 | Atlético MadridVillarreal | |
| 17:00 | Stade Rennais Olympique de Marseille | |
| 17:30 | ChelseaManchester City | |
| 18:00 | Borussia DortmundBayer Leverkusen | |
| 18:00 | Parme Naples | |
| 18:00 | Genk Antwerp | |
| 18:30 | Real Valladolid Bétis Séville | |
| 20:30 | Fiorentina Inter Milan | |
| 20:45 | Levante  Real Madrid | |
| 21:00 | Monaco Olympique Lyonnais | |
