| 20:45 | Le Havre  Troyes |  |
| 21:00 | Bournemouth  Arsenal |  |
| 22:00 | Sporting CP  Maritimo |  |
| 18:30 | Angers  Stade Rennais |  |
| 18:30 | Limonest  Dijon | |
| 18:30 | Belfort  Montpellier | |
| 20:45 | Aston Villa  Leicester City |  |
| 20:55 | Monaco  Saint-Étienne |  |
| 21:15 | FC Porto  Gil Vicente |  |
| 18:30 | Pau  PSG | |
| 18:30 | Épinal  Lille | |
| 20:45 | West Ham United  Liverpool |  |
| 20:45 | Manchester City  Manchester United | |
| 21:05 | Olympique de Marseille  Strasbourg |  |
| 20:55 | Nice  Olympique Lyonnais | |
| 18:00 | Dunkerque  Red Star | |
| 20:00 | Le Havre Lens |  |
| 20:00 | Le Mans  Nancy | |
| 20:00 | Chambly  Caen | |
| 20:00 | Troyes Grenoble Foot 38 |  |
| 20:00 | Rodez  Valenciennes |  |
| 20:00 | Clermont  Orléans |  |
| 20:00 | Guingamp  AJ Auxerre |  |
| 20:00 | AC Ajaccio  Châteauroux | |
| 20:00 | Bastia-Borgo  Gazélec Ajaccio |  |
| 20:00 | Concarneau  Boulogne | |
| 20:00 | Villefranche  Quevilly | |
| 20:00 | Bourg-Péronnas  Toulon | |
| 20:00 | Niort  Paris FC | |
| 20:00 | Créteil  Cholet | |
| 20:00 | Avranches  Le Puy | |
| 20:00 | Laval  Lyon-Duchère | |
| 20:30 | Hertha BSC  Schalke 04 |  |
| 20:45 | Stade Rennais Nantes | |
| 13:00 | Grenade  Espanyol | |
| 13:30 | Hull City  Brentford |  |
| 13:30 | Leicester City Chelsea |  |
| 15:00 | Bologne  Brescia | |
| 15:00 | Caykur Rizespor  Besiktas | |
| 15:30 | Hoffenheim  Bayer Leverkusen | |
| 15:30 | Sochaux  Lorient | |
| 15:30 | Borussia Dortmund  Union Berlin | |
| 15:30 | Fortuna Düsseldorf  Eintracht Francfort | |
| 15:30 | Mainz 05  Bayern Munich |  |
| 16:00 | Real Madrid  Atlético Madrid | |
| 16:00 | Liverpool Southampton | |
| 16:00 | Leeds United  Wigan Athletic | |
| 17:30 | PSGMontpellier | |
| 18:00 | Trabzonspor  Fenerbahçe | |
| 18:30 | Majorque  Real Valladolid | |
| 18:30 | RB Leipzig  Borussia M'gladbach | |
| 18:30 | Manchester United Wolverhampton Wanderers | |
| 20:00 | Angers Reims | |
| 20:00 | Nîmes Monaco | |
| 20:00 | Dijon Brest | |
| 20:00 | StrasbourgLille | |
| 20:00 | Pau Béziers | |
| 20:00 | Amiens SC  Toulouse | |
| 20:45 | Sassuolo  AS Roma | |
| 21:00 | Valence  Celta Vigo | |
| 12:00 | Leganes  Real Sociedad | |
| 12:30 | Juventus  Fiorentina | |
| 14:00 | Eibar  Bétis Séville | |
| 14:30 | Club Bruges  Antwerp |  |
| 15:00 | Milan AC  Hellas Verone | |
| 15:00 | Atalanta  Genoa | |
| 15:00 | Lazio  SPAL | |
| 15:00 | Burnley Arsenal | |
| 15:00 | NiceOlympique Lyonnais | |
| 15:30 | Cologne  Fribourg | |
| 16:00 | Athletic Bilbao  Getafe | |
| 16:45 | Ajax  PSV |  |
| 17:00 | Galatasaray  Kayserispor | |
| 17:00 | Metz Saint-Étienne | |
| 17:30 | Tottenham Hotspur Manchester City | |
| 18:00 | Paderborn  Wolfsbourg | |
| 18:00 | Lecce  Torino | |
| 18:30 | FC Séville  Deportivo Alavés | |
| 20:45 | Udinese  Inter Milan | |
| 21:00 | FC Barcelone  Levante | |
| 21:00 | Bordeaux Olympique de Marseille | |
